I think one of the options of PISA is to calculate accessibilities -- I recall when I was learning how to use pisa that I saw this option.  

Also DSSP outputs accessibilities per residue

Areaimol in ccp4 does too.

I have seen many programs in the internet, google "accessibilities", "accessible surface area."  what_if does something like this too.

On Sun, Jun 19, 2011 at 5:09 PM, VAN RAAIJ , MARK JOHAN <[log in to unmask]> wrote:
Dear Armando,
don't know about NACCESS, but I guess it is superseded by AREAIMOL in CCP4 (also in CCP4i); it outputs the accessible volume per atom in the pdb file and per residue and per chain and some other statistics in the log-file.
Mark

Quoting Armando Albert:

> Does anyone has got some information about how to get a mac version
> (intel), of the old unix program naccess?. It was meant  to calculate
> the solvent accessibility per residue from a pdb file.
> Armando

Mark J van Raaij
Laboratorio M-4
Dpto de Estructura de Macromoléculas
Centro Nacional de Biotecnología - CSIC
c/Darwin 3, Campus Cantoblanco
28049 Madrid
tel. 91 585 4616
email: [log in to unmask]