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Thanks. I was thinking more of the rare situations where a GP would like help with the diagnosis of the disease previously known as myocardial infarction... ... I'm talking to our GPs next week and I don't think that prognostic risk assessment is high on their priorities, but I may be wrong. Jonathan On 16 Jun 2011, at 10:01, David Gaze wrote: > It might be worth holding on to your horses. For the high precision > (sensitivity) assays finding their way on to the market; there seems to > be a valid role for hs-cTn measurement for prognostic risk assessment in > the primary care setting. > > See: > > Apple FS. High Sensitivity Cardiac Troponin for Screening Large > Populations of Healthy People: Is there a risk? Clin Chem > 2011;57:537-539 > > deFilippi CR, de Lemos JA, Christenson RH, Gottdiener JS, Kop WJ, Zhan > M, Seliger SL. Association of serial measurement of cardiac troponin T > using a sensitive assay with incident heart failure and cardiovascular > mortality in older adults. JAMA > 2010;304:2494 -502. > > de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. > Association of troponin T detected with a highly sensitive assay and > cardiac > structure and mortality risk in the general population. JAMA > 2010;304:2503-12. > > Blankenberg S, Zeller T, Saarela O, Havulinna AS, Kee F, Tunstall-Pedoe > H, et al. Contributions of 30 biomarkers to 10-year cardiovascular risk > estimation in 2 population cohorts: the MONICA, Risk Genetics, > Archiving, and Monograph > (MORGAM) Biomarker Project. Circulation 2010;121:2388 -97. > > Apple FS, Steffen LM, Pearce LA, Murakami MM, Luepker RV. Multiple > biomarkers for prediction of cardiovascular death within the Minnesota > Heart Survey [Abstract 17337]. Circulation 2010; 122(Suppl):23. > > > ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/