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It might be worth holding on to your horses. For the high precision (sensitivity) assays finding their way on to the market; there seems to be a valid role for hs-cTn measurement for prognostic risk assessment in the primary care setting. See: Apple FS. High Sensitivity Cardiac Troponin for Screening Large Populations of Healthy People: Is there a risk? Clin Chem 2011;57:537-539 deFilippi CR, de Lemos JA, Christenson RH, Gottdiener JS, Kop WJ, Zhan M, Seliger SL. Association of serial measurement of cardiac troponin T using a sensitive assay with incident heart failure and cardiovascular mortality in older adults. JAMA 2010;304:2494 -502. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010;304:2503-12. Blankenberg S, Zeller T, Saarela O, Havulinna AS, Kee F, Tunstall-Pedoe H, et al. Contributions of 30 biomarkers to 10-year cardiovascular risk estimation in 2 population cohorts: the MONICA, Risk Genetics, Archiving, and Monograph (MORGAM) Biomarker Project. Circulation 2010;121:2388 -97. Apple FS, Steffen LM, Pearce LA, Murakami MM, Luepker RV. Multiple biomarkers for prediction of cardiovascular death within the Minnesota Heart Survey [Abstract 17337]. Circulation 2010; 122(Suppl):23. Disclaimer: This e-mail and any files transmitted with it are confidential. If you are not the intended recipient, any reading, printing, storage, disclosure, copying or any other action taken in respect of this e-mail is prohibited and may be unlawful. If you are not the intended recipient, please notify the sender immediately by using the reply function and then permanently delete what you have received. Incoming and outgoing e-mail messages are routinely monitored for compliance with the Department of Health's policy on the use of electronic communications. For more information on the Department of Health's e-mail policy click here http://www.doh.gov.uk/emaildisclaimer.htm ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/