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MEDICAL: DISEASES: DIABETES:
NIH Announces New Strategic Plan to Combat Diabetes

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Date: Fri, 18 Mar 2011 10:52:56 -0400
From: "NIH OLIB (NIH/OD)" <[log in to unmask]>
To: [log in to unmask]
Subject:  NIH Announces New Strategic Plan to Combat Diabetes

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U.S. Department of Health and Human Services
NATIONAL INSTITUTES OF HEALTH NIH News

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National Institute of Diabetes and Digestive and Kidney Diseases
(NIDDK)

http://www.niddk.nih.gov/

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For Immediate Release: Friday, March 18, 2011

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CONTACT:

Rita Zeidner

301-496-3583

e-mail:

[log in to unmask]>

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NIH ANNOUNCES NEW STRATEGIC PLAN TO COMBAT DIABETES

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Multiple stakeholders tapped to develop roadmap for preventing, treating 
and finding a cure

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A new strategic plan to guide diabetes-related research over the next 
decade was announced today by the National Institutes of Health.  The 
plan, developed by a federal work group led by the National Institute of 
Diabetes and Digestive and Kidney Diseases (NIDDK), identifies research 
opportunities with the greatest potential to benefit the millions of 
Americans who are living with or at risk for diabetes and its 
complications.

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"By setting priorities and identifying the most compelling research 
opportunities, the strategic plan will guide NIH, other federal agencies 
and the investigative community in efforts to improve diabetes treatments 
and identify ways to keep more people healthy," said NIDDK Director 
Griffin P. Rodgers, M.D.

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The plan, Advances and Emerging Opportunities in Diabetes Research: A 
Strategic Planning Report of the Diabetes Mellitus Interagency 
Coordinating Committee, focuses on 10 areas of diabetes research with the 
most promise. The goal is to accelerate discovery on several fronts, 
including:

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-- the relationship between obesity and type 2 diabetes, and how both 
conditions may be affected by genetics and environment

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-- the autoimmune mechanisms at work in type 1 diabetes

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-- the biology of beta cells, which release insulin in the pancreas

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-- development of artificial pancreas technologies to improve management 
of blood sugar levels

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-- prevention of complications of diabetes that affect the heart, eyes, 
kidneys, nervous system and other organs

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-- reduction of the impact of diabetes on groups disproportionately 
affected by the disease, including the elderly and racial and ethnic 
minorities

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Under the plan, NIH will continue to emphasize clinical research in 
humans, which already has led to highly effective methods for managing 
diabetes and preventing complications, Rodgers said.

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The NIH strategy for fighting diabetes addresses type 1 and type 2 
diabetes. Type 1 diabetes, which affects about 5 percent of individuals 
with diagnosed diabetes, is an autoimmune disease that most often develops 
during childhood. Type 2 diabetes accounts for 90 to 95 percent of 
diagnosed diabetes cases in the United States, and is strongly associated 
with overweight and obesity. In addition, the plan addresses gestational 
diabetes, a condition that some women develop during pregnancy, but which 
usually goes away after their child is born. Women who develop gestational 
diabetes during pregnancy are at increased risk for developing type 2 
diabetes, and the child of that pregnancy may also be at increased risk 
for obesity and type 2 diabetes.

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Today, about 1 in 10 adults in the United States has diabetes, according 
to the Centers for Disease Control and Prevention. About 1.9 million 
Americans aged 20 years or older were newly diagnosed with diabetes in 
2010. In addition, an estimated 79 million American adults have 
pre-diabetes, a condition in which blood sugar levels are higher than 
normal but not high enough to be diagnosed as diabetes.  By 2050, as many 
as 1 in 3 adults could be diagnosed with diabetes if current trends 
continue, according to the CDC. The projection assumes that recent 
increases in new cases of diabetes will continue and people with diabetes 
will also live longer, which adds to the total number of people with the 
disease.

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Diabetes eventually damages nearly every organ system in the body. People 
with diabetes are at increased risk for blindness, kidney failure, and 
lower limb amputation. Overall, the risk for death among people with 
diabetes is about twice that of people of similar age without diabetes. In 
addition, it is a very expensive disease to manage. Total costs of 
diabetes, including medical care, disability, and premature death, reached 
an estimated $174 billion in 2007 in the United States.

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The plan was developed by the Diabetes Mellitus Interagency Coordinating 
Committee (DMICC)

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http://www2.niddk.nih.gov/AboutNIDDK/CommitteesAndWorkingGroups/DMICC/

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a congressionally authorized workgroup chaired by the NIDDK.  Established 
in 1974, the DMICC facilitates cooperation, communication, and 
collaboration on diabetes research across the federal government.  Key 
elements of the report were identified by multiple public and private 
stakeholders, including representatives of DMICC member agencies, health 
advocacy groups and external scientists who are leaders in the diabetes 
research field.  To ensure broad input, a draft of the strategic plan was 
also posted for public comment prior to publication.  The strategic plan 
is available electronically at

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http://diabetesplan.niddk.nih.gov/

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Printed copies can be requested from the National Diabetes Information 
Clearinghouse beginning April 1, 2011, at

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1-800-860-8747

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and by email at

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[log in to unmask]

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Single copies are free.

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The NIDDK, a component of the National Institutes of Health (NIH), 
conducts and supports research on diabetes and other endocrine and 
metabolic diseases; digestive diseases, nutrition and obesity; and kidney, 
urologic and hematologic diseases. Spanning the full spectrum of medicine 
and afflicting people of all ages and ethnic groups, these diseases 
encompass some of the most common, severe and disabling conditions 
affecting Americans. For more information about the NIDDK and its 
programs, see

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http://www.niddk.nih.gov

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The National Institutes of Health (NIH) -- The Nation's Medical Research 
Agency -- includes 27 Institutes and Centers and is a component of the 
U.S. Department of Health and Human Services. It is the primary federal 
agency for conducting and supporting basic, clinical and translational 
medical research, and it investigates the causes, treatments, and cures 
for both common and rare diseases. For more information about NIH and its 
programs, visit

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http://www.nih.gov

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This NIH News Release is available online at:

http://www.nih.gov/news/health/mar2011/niddk-18.htm

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