Hi - as the others have suggested, you can do a "resting state" (i.e. resting functional connectivity) analysis without assuming that the brain is in the "normal" resting state. In such experiments people sometimes split the session into different blocks (e.g. before, during, after infusion) and compare the connectivities within those blocks with each other……but there are many confounds to worry about, such as whether apparent correlation changes are neural or vascular changes.

Cheers.

On 23 May 2011, at 20:58, Claudia Huerta wrote:

Hi,

I'm trying to asses the changes on resting state networks after a drug infusion. The drug infusion last around 10 minutes.
Is it OK to treat the data during the infusion as Resting state data?
Thanks

Ivette

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