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Hi Angela
 
We also seem to have moved very rapidly to the apparent abandonment of 'pre-diabetes' (usually regarded as being IFG and/or IGT) according to p4 of the full guidance:

         The referral [to NICE from the DoH]……originally set out to address the prevention of ‘pre-diabetes’ among adults.

         However, in January 2011 the WHO recommended that HbA1c could be used as an alternative to standard glucose measures to diagnose type 2 diabetes ….but there is no fixed point to indicate when someone has ‘pre-diabetes’.

         The title of this guidance has been changed since it went out for consultation to reflect this move away from recognising ‘pre-diabetes’ as a separate condition.

 
Which is an interesting interpretation of the actual WHO wording:
 

'An HbA1c of 6.5% is recommended as the cut point for diagnosing diabetes.

A value less than 6.5% does not exclude diabetes diagnosed using glucose

tests. The expert group concluded that there is currently insufficient evidence

to make any formal recommendation on the interpretation of HbA1c levels

below 6.5%.'

 

Eric

Professor E S Kilpatrick
Department of Clinical Biochemistry
Hull Royal Infirmary
Anlaby Road
Hull HU3 2JZ

Tel 01482-607708
Fax 01482-607752



 


Date: Tue, 10 May 2011 15:13:56 +0100
From: [log in to unmask]
Subject: HbA1c in diagnosis of DM (2)
To: [log in to unmask]

From the latest NICE guideline ‘Preventing Type 2 Diabetes’:

 

“Type 2 diabetes is diagnosed in adults who are not pregnant by a glycated haemoglobin (HbA1c) level of 6.5% (48 mmol/mol) or above.

  A type 2 diabetes diagnosis can also be made by:

 

Does anyone else think that we went very quickly from HbA1c can be used for the diagnosis of DM to it being the first line test?

 

Regards,

 

Angela

Angela Kremmyda

Senior Biochemist

 

Dept of Clinical Biochemistry

Royal Shrewsbury Hospital

Mytton Oak Road

Shrewsbury

SY3 8XQ

 

Tel:  01743 261158

Fax: 01743 261159

 

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