Hi, I am using a task that involves hearing the same story four times followed by two different tasks. I am attempting to look at habituation effects for the repeated story- so areas where activation decreases as the task is repeated. For this contrast I have conducted an ANOVA. The contrast I specified is: 1 -1 0 0 0 0 0 1 -1 0 0 0 0 0 1 -1 0 0 The problem is when I use this contrast I get one giant whole-brain cluster (figure attached). When I conduct individual t-tests, such as 1 -1 0 0 0 0 or 0 1 -1 0 0 0, I don't see any abnormal activation. Does anyone know what might be going on here? Also might anyone know a better way of looking at habituation effects? Thank you, Meera Meera Paleja, B.Sc. (Hons.), M.A. PhD. Student, Psychological Science Brain Imaging and Memory Lab Department of Psychology Ryerson University Phone: (416) 979-5000 ex. 2192 email: [log in to unmask] “Perhaps the most fascinating and mysterious universe of all is the one within us.” -- Carl Sagan