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You should use the flexible factorial model for this. If you search the list, you will find a document by Glascher and Gitelman with details on how to set this model up. The only caveat, and this applies to the full factorial as well, is that the statistics for the group factor are not valid. The time and group*time inferences are valid. For inference on the group factor, you need to first average the pre- and post-treatment values. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Postdoctoral Research Fellow, GRECC, Bedford VA Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Tue, Apr 19, 2011 at 11:09 AM, Kelly Nash <[log in to unmask]> wrote: > Hello! > > Hoping someone can help, I am new to SPM and am trying to utilize a full > factorial design to test the effects of a treatment, using a go nogo task. > > > I am using SPM5. I have 2 groups and two time points; I want to look at the > nogo minus go contrast taking into account the effect of time, group and the > group*time interaction. > > Can someone please help clarify what needs to get entered into the design > and which of the automatic contrasts produced by SPM that I should be > looking at. > > Thanks! > > > > Kelly Nash M.A. > PhD Candidate > Ontario Institute for Studies in Education/University of Toronto > Neuroscience and Mental Health Program > Rovet Lab, Rm 6406 > The Hospital for Sick Children > 555 University Avenue > Toronto ON, Canada, M5G1X8 >