Carl Henegan of CEBM Oxford has just posted to his blog "..a list of what I think are the top ten the most influential epidemiological studies.. Rules are it has to be a clinical study that involves people, which excludes basic sciences. In addition the study has to have subsequently influenced the field significantly."

A starter for 10....

Gary

___________________________________________________________________________
Gary Jackson, Clinical Director Health Intelligence Counties Manukau District Health Board
19 Lambie Drive, Manukau City Private Bag 94052, South Auckland Mail Centre
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From: Evidence based health (EBH) [mailto:[log in to unmask]] On Behalf Of Jon Brassey
Sent: Monday, 4 April 2011 22:53
To: [log in to unmask]
Subject: Landmark clinical papers

Hi All,

I have a feeling that this question has been asked before on this list, but is anyone aware of a list of landmark clinical papers that have had a 'significant' impact on clinical practice? I'm thinking of primary research such as the 4S simvastatin study and/or secondary research such as streptokinase post-MI. If there is no list, might it be useful to create one?

I do appreciate the difficulty of defining what constitutes 'landmark' or 'significant impact'!

Best wishes

jon

Jon Brassey

TRIP Database

http://www.tripdatabase.com

TILT

http://tilt.tripdatabase.com

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