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I wonder whether that is why it works as an anti-coagulant? Is it mimicking nucleic acids? So then would DNA work as an anti-coagulant as well...? JPK On Mon, Apr 11, 2011 at 4:20 PM, Nian Huang <[log in to unmask]> wrote: > Heparin simulates the structure of DNA and RNA, so it has nonspecific > affinity towards DNA or RNA binding protein. It has also been used as DNAse > or RNase inhibitor but it is not very good one. > > Nian Huang, Ph.D. > UT Southwestern Medical Center > > On Sat, Apr 9, 2011 at 7:44 PM, Alexandra Deaconescu <[log in to unmask]> > wrote: >> >> Hello ccp4 enthusiasts: >> >> I am afraid this is a non-ccp4 related question. Can anyone recommend an >> immobilized dsDNA chromatographic resin for purification of DNA-binding >> proteins? GE seems to have something - I was wondering if people have other >> recommendations? In the age of GST and His tags etc., these are not very >> much used, but I do not have a tag in this case... >> >> Thanks a lot, >> Alex > > -- ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program cel: 773.608.9185 email: [log in to unmask] *******************************************