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Hi Kenneth,

I hope this will answer most of your questions:

http://www.phenix-online.org/newsletter/

see "TLS for dummies" and "On atomic displacement parameters..." articles.

Pavel.


On Thu, Apr 7, 2011 at 5:39 PM, Kenneth A. Satyshur <[log in to unmask]>wrote:

> peoples:
>
> I know that TLS is a group B factor for regions of proteins that are moving
> the same.
> It is used in low res structures. But at what resolution does one begin
> anisotropic, i.e
> individual aniso for each atom, and leave TLS out. Or can one still use TLS
> to first
> compensate for large motions and then dampen down the individual atoms with
> aniso ADP?
> If both the aniso and TLS are used, how does a person interpret the
> results? What programs
> are there to see just what is large body motions and what is atoms.
> thanks
>
> --
> Kenneth A. Satyshur, M.S.,Ph.D.
> Associate Scientist
> University of Wisconsin
> Madison, Wisconsin 53706
> 608-215-5207
>