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Hi SPM-ers, I am seeing odd activation patterns in my data, specifically "dalmation-like" activation, where one or two voxel "clusters" are activated throughout the brain, with very few clusters larger than that. Does anyone know what might account for this? I haven't smoothed the data as I am interested in very small regions (hippocampal subregions)- could the lack of smoothing be a reason for these strange patterns? Thanks! Meera Meera Paleja, B.Sc. (Hons.), M.A. PhD. Student, Psychological Science Brain Imaging and Memory Lab Department of Psychology Ryerson University Phone: (416) 979-5000 ex. 2192 email: [log in to unmask] “Perhaps the most fascinating and mysterious universe of all is the one within us.” -- Carl Sagan