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Only place in the SPM8 code I see for that warning is this bit from spm_getSPM.m:


====begin code snippet====

%-Check the model has been estimated
%--------------------------------------------------------------------------
try
    SPM.xVol.XYZ;
catch
    
    %-Check the model has been estimated
    %----------------------------------------------------------------------
    str = { 'This model has not been estimated.';...
            'Would you like to estimate it now?'};
    if spm_input(str,1,'bd','yes|no',[1,0],1)
        SPM = spm_spm(SPM);
    else
        SPM = []; xSPM = [];
        return
    end
end

====end code snippet====

So...if you start matlab and type
    load SPM
and then type
    SPM.xVol
what do you see?  (Sounds like a corrupted or otherwise incorrect SPM.mat file.)