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Dear SPM Community, While analyzing results from a recent fMRI study, I have discovered that I have very little activation in the lower regions of the brain. I am concerned that SPM may have truncated my data in the lower regions of the brain because they were below threshold. Since I am particularly interested in activation in the OFC, this is a problem. Upon reviewing my data (ie. mask.img), it looks like SPM cut out brain activity in the OFC after first-level analysis. To resolve this issue, I am thinking of trying to force SPM to use an explicit mask of the entire brain. Does anyone know how to implement this in script format? Alternatively, if anyone has better ideas on how to improve signal in the OFC, please let me know. Many thanks in advance for all your help! Deborah Tang, Doctoral Candidate McGill University Montreal Neurological Institute 3801 University St, Room WB 214D Montreal, QC H3A 2B4 Canada Phone: (514) 398-6644 Ext. 089469 Fax: (514) 398-8948 [log in to unmask]