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Hi, I wanna do regression analysis between FA map and behavioral data with age and sex as covariaters using randomise. I have two questions to ask. First, I have designed matrix using GLM. Group EV1(behav) EV2(sex) EV3(age) 1 3.2 0 15 1 5.3 0 18 1 4.2 1 18 1 5.2 1 17 1 4.9 1 17 And the contrast: EV1 EV2 EV3 1 0 0 I want to know the matrix is correct or not. Second, does is it need to demean my data using the parameter ¡®¨CD¡¯ when runing randomise. Thanks a lot, Haitao ------------------------------------------------------- Haitao Ge, Ph.D. Center for Sectional and Imaging Anatomy Shandong University School of Medicine 44#, West Wenhua Rd. Jinan 250012, Shandong P.R.China Tel: +86-15965644699 Email: [log in to unmask]