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Hi Josselin,

If you have two groups (2 controls and 3 patients here) and are looking at the differences between the two with an additional covariate, what I mean by "model the mean" is something like:

1 0 -4
1 0 2
0 1 -2
0 1 0
0 1 4

(then there is no need of -D in randomise)

instead of:

1.2  -4
1.2  2
-0.8 -2
-0.8 0
-0.8 4

(in which case you need -D in randomise)


Cheers,
Gwenaelle


> De: Josselin Houenou <[log in to unmask]>
> Objet: Re: [FSL] Re : [FSL] Covariables and demean
> À: [log in to unmask]
> Date: Samedi 12 mars 2011, 17h04
> Hi Gwenaelle,
> 
> I have a quite trivial question about your answer. Let's
> assume all the covariables have been demeaned. You say that
> "run randomise with the -D option if you have not modelled
> the mean for each group". What do you mean by "model the
> mean for each group" ?
> 
> Thanks,
> Josselin

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Gwenaëlle Douaud, PhD

FMRIB Centre, University of Oxford
John Radcliffe Hospital, Headington OX3 9DU  Oxford  UK

Tel: +44 (0) 1865 222 523  Fax: +44 (0) 1865 222 717

www.fmrib.ox.ac.uk/~douaud

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