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Dear Ben,


You will get the answer to your computer question at:
http://www.top500.org/lists/2010/11/press-release

I don't know whether you have read recently about IBM's Computer 'Watson' 
beating the best players on the 'Jeopardy' TV programme in the USA:
http://www.pcworld.com/article/220056/watson_beats_jeopardys_best_whats_next.html

Apparently, this machine costs 3 million dollars today, but by 2020, we will be 
able to get them for a few thousand dollars each.

Regards,

 
Ash 
Dr Ash Paul
Medical Director
NHS Bedfordshire
21 Kimbolton Road
Bedford
MK40 2AW
Tel no: 01234897224
Email: [log in to unmask]
 





________________________________
From: "Djulbegovic, Benjamin" <[log in to unmask]>
To: [log in to unmask]
Sent: Thu, 24 March, 2011 23:49:55
Subject: Re: Clinical Decision Making and Diagnostic Error

perhaps we identify with the conscious but not with the non-conscious because we 
consider technological and other advances as an integral part of our logical, 
conscious system...but I don't believe that with all inventions at our disposal 
we are close to processing 10,000,000 bits of information per second (and 
without overheating!)
BTW, what is the fastest modern computer in terms of processing power?
ben

________________________________________
From: Jim Walker [[log in to unmask]]
Sent: Thursday, March 24, 2011 4:13 PM
To: Djulbegovic, Benjamin; [log in to unmask]
Subject: Re: Clinical Decision Making and Diagnostic Error

The non-conscious system is massively parallel and processes something on the 
order of 10,000,000 bits of information per second, the conscious between 16 and 
32 bits.
So the conscious is something like the tip of a fully integrated iceberg, 
dependent on the pre-processing of disparate inputs by the non-conscious system 
for the highly (and necessarily) filtered information which it manipulates.
So while the conscious can direct the attention of some aspects of the 
non-conscious system to some extent, there is no theoretical or empiric reason 
to think that the conscious system can "train" the non-conscious--or that we 
would benefit if it could. (Interesting how we identify with the conscious but 
not with the non-conscious.)

Jim

James M. Walker, MD, FACP
Chief Health Information Officer
Geisinger Health System


>>> "Djulbegovic, Benjamin" <[log in to unmask]> 3/24/2011 3:31 PM >>>

Hi Amy,
I am at the moment reading some papers by Read Montague (from Baylor)...
He has written some interesting stuff...
Best
ben

From: Dr. Amy Price [mailto:[log in to unmask]]
Sent: Thursday, March 24, 2011 3:13 PM
To: Djulbegovic, Benjamin; [log in to unmask]
Subject: RE: Clinical Decision Making and Diagnostic Error

Dear Ben ,Neal and all,

I am interested in the fMRI data identifying discrete brain areas for systems 1 
and 2. I am particularly intrigued by how/when they link and if the unconscious 
bias might be trained .  Do you have authors names, links or papers you could 
share. I am looking at this area in regards to addiction and collaborating with 
others who are identifying genomics. Presently exploring QEEG to see if this 
uncovers anything of interest...

Best regards,
Amy

From: Evidence based health (EBH) [mailto:[log in to unmask]] 
On Behalf Of Djulbegovic, Benjamin
Sent: 24 March 2011 02:55 PM
To: [log in to unmask]
Subject: Re: Clinical Decision Making and Diagnostic Error


Neal,
Thanks for these insights - it is a really interesting thought about the fMRI 
data identifying discrete brain areas as location of system 1 and system 2 (at 
the moment, I am too reading on this fascinating stuff, and after you pointed 
this out, I wonder what would Hammond say about the empirical data that seems to 
be falsyfying his thesis?)
Regarding which reasoning system gets its more right than wrong, I think we are 
saying the same thing, except (that in my reading of Hammond he seems to be 
saying) that when we get it wrong, the consequences of relying on intuition vs. 
logic are of the magnitude order less significant? (We are, of course, talking 
about decisions related to human affairs and social policies, not to the stuff 
in the realm of the quantum physics!)
Best
ben

From: Evidence based health (EBH) [mailto:[log in to unmask]] 
On Behalf Of Maskrey Neal
Sent: Thursday, March 24, 2011 2:04 PM
To: [log in to unmask]
Subject: Re: Clinical Decision Making and Diagnostic Error

Ben

Good to hear from you. Spring's arrived in England and it's lovely, but it sure 
ain't Florida!

My reading is slightly different. From that, neither system 1 nor system 2 are 
superior, but system 1 is our "default". If we are talking about errors of 
commission, then then Pat Coskerry shows these occur predominately in system 1 
due to the common cognitive and affective biases. My own personal dramatic 
memories are fortunately few in number, but when I got it wrong the usual 
contributing factors were availability bias and  affective - notably work 
overload and sleep deprivation. And I'm sure Hammond isn't right about us never 
being spectacularly wrong in system 1. In system 2 the common problem is 
omission - if a common medical emergency presents it isn't optimal to have to 
spend lots of time working out the diagnosis and treatment plan. Broadly 
speaking, as Pat Croskerry says, we're safer in system 2 - but we're a lot 
slower.

The MRI emission data identifies particular and quite different areas of the 
brain being used live with system 1 and system 2 decision making and that's 
harder to explain as a continuum - happy to debate. We've obviously "cartooned" 
some of this necessarily in these brief, awareness-raising group discussions and 
one of the facets we've not mentioned is the frequent live toggling in decision 
making between system 1 and system 2.

The key trick is to train people to step back and re-examine the issue...both 
from logical (system 2) and affective side (system 1)...a tough to do when 
decisions have to be made in a short time-frame...

Absolutely. The next step is to prove teaching these approaches changes 
behaviour, and then that change in behaviour improves the processes used in 
decision making if that's possible. Showing improved outcomes or less errors or 
both would be ideal, but if we're honest the definitive literature showing 
"teaching EBM" or for that matter teaching anatomy or teaching genetics improves 
outcomes isn't massive either. The quick "could this be anything else" or "are 
there any other / better treatment options" or "did I check for 
contraindications / interactions" calibration at the end of the consultation is 
simply plain old fashioned good medical practice, so if this is well presented 
its (a) an interesting subject to teach and learn, and (b) some of the content 
has excellent face validity for students. Likewise the more leisurely reflection 
- but then maybe the St Pete police would want drivers to be concentrating on 
the road!

I keep hearing about on going research which might move all of this forward, and 
there's certainly lots of interest. Fabulous.

Best

Neal

Neal  Maskrey
National Prescribing Centre
Liverpool UK

________________________________
From: Evidence based health (EBH) [mailto:[log in to unmask]] 
On Behalf Of Djulbegovic, Benjamin
Sent: 24 March 2011 11:02
To: [log in to unmask]
Subject: Re: Clinical Decision Making and Diagnostic Error


Neal, a challenge is, of course, to know when to use our intuitive (system 1) 
vs. logical (system 2) inferential process...Kenneth Hammond, who has promoted 
idea of a continuum between system 1 and system 2 (instead two sharply 
demarcated systems), has made a point that if we rely on the system 1, we will 
often be more wrong than right, but never spectacularly wrong. On other hand, 
reasoning based on system 2 (this would include EBM) would be more often right, 
but when it is wrong it can be phenomenally wrong (as our models of the world 
can be hugely mistaken)... A practical/educational corrolary from this is "rely 
on EBM, but if it does not agree with your intuition, don't go there 
go/re-examine your decision..."  The key trick is to train people to step back 
and re-examine the issue...both from logical (system 2) and affective side 
(system 1)...a tough to do when decisions have to be made in a short 
time-frame...My own approach has been to ask students/residents/fellows is a) to 
review mentally all patient'stories ("cases") at the end of the day and focus on 
any possible oversights/errors that may occurred that day (e.g. while driving 
back home), b) ask yourself " if I were the patient, would I like to be taken 
care by thy guy/girl like me?"

I have been doing this for years- wish I can report that I found the 
"solution"...unfortunately, I still find myself much deficient as I try to 
answer these questions...but resoluted to do better next day...

ben djulbegovic