Did you repeat the low value (17 nmol/l) from the Liaison on the
Liaison?
Kent C. Dooley PhD FCACB
Clinical Chemist
LifeLabs
3201 - 4464 Markham Rd.
Victoria BC V8Z 7X8
tel: 250 881-3100 ext. 2120
email: [log in to unmask] <mailto:[log in to unmask]>
web: www.LifeLabs.com <http://www.lifelabs.com/>
________________________________
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of Walsham Natalie
(LEWISHAM HEALTHCARE NHS TRUST)
Sent: Wednesday, March 09, 2011 8:07 AM
To: [log in to unmask]
Subject: Abbott Vitamin D method
Dear all
I apologise for sending yet another email about vitamin D methods but I
am hoping to get feedback from anyone evaluating or routinely using the
new Abbott Architect 25-OH vitamin D assay.
We evaluated the Architect method (twice) against the DiaSorin LIAISON
25-OH vitamin D assay and found the Abbott results to have a positive
bias with a y intercept of 14nmol/L even after major outliers were
removed. Abbott claim that no other user has seen this positive bias and
that if there was significant 25-OH D2 in the samples then the Architect
should give lower results than the Liaison, and that other precursors
should not react in the Architect assay.
There was also a substantial difference between methods for a couple of
samples. One sample gave a result of 17 nmol/L on the Liaison and 121
nmol/L on the Architect!!!
I would be grateful to hear from other Architect users and their
experience of the vitamin D method.
Many thanks
Regards
Natalie
Natalie Walsham DipRCPath
Lead Clinical Scientist
University Hospital Lewisham
Tel: 020 3192 6980
<http://www.kingspath.co.uk/>
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