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Hi there i have modeled a ribavirin molecule in one of the structures that i solved at 2.5A recently. omit map confirms the presence of ligand but the map itself is not very clear.there is some positive density in fo-fc map around the ribose ring, that disappears at 3.2sigma level. I wonder whether it is possible that the ribose ring has exo(2' and 3') and endo(2' and 3') conformation in the model. from where can i get the coordinates of these conformations of ribavirin. or how can i draw this using sketcher in ccp4. can anyone please send me the smileys of these two conformations. any other suggestions are also welcome. regards and thanks in advance, -- INTEKHAB ALAM LABORATORY OF STRUCTURAL BIOINFORMATICS KOREA UNIVERSITY, SEOUL