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Hi, in my updated VBM8 manual the group and time factors were not correctly defined in the interaction design on page 21-22. The columns and rows have to be switched (or the array transposed). Thanks to Pieter van de Vijver for finding this error. The manual is now corrected and can be found at: http://dbm.neuro.uni-jena.de/vbm8/VBM8-Manual.pdf Regards, Christian ____________________________________________________________________________ Christian Gaser, Ph.D. Departments of Psychiatry and Neurology Friedrich-Schiller-University of Jena Jahnstrasse 3, D-07743 Jena, Germany Tel: ++49-3641-934752 Fax: ++49-3641-934755 e-mail: [log in to unmask] http://dbm.neuro.uni-jena.de