Claire,

These are 2 separate issues. 

The inclusion of the temporal or dispersion derivatives captures variance in the response in the cases where neural activity is shift in time of onset or duration. You can think of this as capturing more of the signal in the data.

The inclusion of motion parameters is to account for shifts in signal due to motion. You can think of this as reducing the noise in the data.

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Postdoctoral Research Fellow, GRECC, Bedford VA
Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School
Office: (773) 406-2464
=====================
This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email.


On Sun, Jan 2, 2011 at 4:45 PM, Claire (Jung Eun) Han <[log in to unmask]> wrote:
Hello,

This question is regarding the first model specification.
Is it preferred to choose HRF only (without time or/and dispersion derivatives) when we add realignment parameters as multiple regressors? If so, why?

Thanks,
Claire