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POSTDOCTORAL POSITION IN PROTEOMICS / CELLULAR BIOLOGY FOCUSED ON THE ROLE OF NUCLEAR LAMINS IN THE RESPONSE TO OXYDATIVE STRESS A new postdoctoral position is becoming available at CEA, a research institute located in the south-west suburb of Paris. The postdoctoral project aims at determining essential molecular mechanisms linking genome spatial organization and genome integrity. It is focused on the elucidation of the role of nuclear lamins in the response to oxidative stress. It will be carried out at the interface between two teams of complementary expertises: (1) the team of Pascale Bertrand, which recently characterized lamin defaults in cells deficient in DNA damage signalling proteins on the basis of cell biology experiments and is running a proteomic core facility to detect partners from 2D gels of complexes; (2) the team of Sophie Zinn-Justin, which has determined the 3D structures of several nuclear envelope protein domains as in particular the lamin C-terminal domain and is now involved in the characterization at the atomic level of interactions between these domains and their biological partners. Experience in cell biology and/or biochemistry is essential. The candidate should also be interested by molecular aspects and biophysics. Competitive salary (2230 euros for the fellow, i.e. 2800 euros comprising the social taxes, per month or more, based on previous research experience) is offered with health insurance, retirement plan, and language training allowance. Starting date is flexible. Interested candidates should forward a Curriculum Vitae, and electronic and postal addresses of potential references via e-mail: [log in to unmask] and [log in to unmask] Dr Sophie Zinn-Justin CEA/DSV/IBiTec-S Laboratoire de Biologie Structurale et Radiobiologie bat 144, CE Saclay 91191 Gif-sur-Yvette FRANCE email : [log in to unmask] tel: (33) (0)1 69 08 30 26