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Ensure that you coregister the fMRI with the reoriented anatomical scan (use check reg to see if it works). Also note that if you segment the anatomical scan first, you'll need to have an fMRI scan as source image, the anatomical as reference and all the fMRI as other. Best regards, -John On 8 December 2010 02:51, junhai xu <[log in to unmask]> wrote: > Dear SPMers, > > We have got a problem in segmentation when normalizing the fMRI data. > > We make a reorientation after the segmentation doesn't work so well. But the > fMRI data have also changed a lot > after writing the seg_*sn.mat to the fMRI data. I don't know what I should > do. > > Thanks a lot for your reply. > > Junhai > > -- > Junhai Xu > Research Center for Sectional and Imaging Anatomy > Shandong University School of Medicine > No. 44, West Wenhua Road, Jinan, Shandong > 250012 P.R. CHINA > > Tel: +86-531-8838 2093 > >