 |
 |
Hello again, I have reviewed the matrix and find the mistake in EV1. Sorry for the long mail. Cheers, Patricia 2010/12/27 SUBSCRIBE FSL Patricia Pires <[log in to unmask]> > Hello! > > Can anyone help with the Glm design matrix? > > I have 3 groups: Healthy control, premutation patients (without the > disease) and patients who have developed the disease. The hypotesis is: the > less FA value, the greater group's severity will be. > > I did statistical analysis and i have to include age and gender in Glm > matrix. > > The steps in the design matrix are: > > 1) Number of original EV's = 9 (3 for the groups, 3 for gender, 3 for age) > > 2) Classify the groups according to the order they are in origdata: > > Group 1 --> Healthy Control > Group 2 --> Patients with the Disease > Group 3 --> Premuted > > 3) Numerate 1 in the corresponding EV's if they below to the group > (EV1=healthy group, EV2=Patients with Disease group and EV3=Premuted group) > if they don't below to the group, numerate with 0. > 4) Numerate 1 or 2 (if they are Males=1 or Females=2) in the corresponding > EV4=gender healthy , EV5=gender Disease, EV5= gender Premuted. If they dont > below the group numerate with 0. > 5) Numerate the age in EV6= age healthy, EV7=age Disease and EV9= age > Premuted. Again,if they don't below to the corresponding group, numerate > with 0. > > /Matrix > 1.000000e+00 0.000000e+00 0.000000e+00 2.000000e+00 > 0.000000e+00 0.000000e+00 7.500000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 6.700000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 5.400000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 3.400000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 3.700000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 2.000000e+00 > 0.000000e+00 0.000000e+00 4.600000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 3.500000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 2.000000e+00 > 0.000000e+00 0.000000e+00 3.900000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 2.000000e+00 > 0.000000e+00 0.000000e+00 5.100000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 7.200000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00 > 0.000000e+00 0.000000e+00 6.100000e+01 0.000000e+00 > 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 2.000000e+00 > 0.000000e+00 0.000000e+00 7.800000e+01 0.000000e+00 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 7.100000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 7.200000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 2.000000e+00 0.000000e+00 0.000000e+00 4.400000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 2.000000e+00 0.000000e+00 0.000000e+00 7.700000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 2.000000e+00 0.000000e+00 0.000000e+00 6.700000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 7.900000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 7.900000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 6.500000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 2.000000e+00 0.000000e+00 0.000000e+00 7.600000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 2.000000e+00 0.000000e+00 0.000000e+00 6.100000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 2.000000e+00 0.000000e+00 0.000000e+00 5.600000e+01 > 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 0.000000e+00 0.000000e+00 6.100000e+01 > 0.000000e+00 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 3.700000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 3.600000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 4.600000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.800000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.400000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 6.500000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 5.600000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.900000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.800000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 8.100000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 4.300000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 6.900000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 6.200000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.200000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.300000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 4.900000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 3.800000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 5.000000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 4.200000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 3.800000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 4.900000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 4.300000e+01 > 1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 > 0.000000e+00 2.000000e+00 0.000000e+00 0.000000e+00 > 3.900000e+01 > > > Then, 6 contrast: > > /ContrastName1 Control>Premut > /ContrastName2 Control<Premut > /ContrastName3 Control>Disease > /ContrastName4 Control<Disease > /ContrastName5 Premut>Disease > /ContrastName6 Premut<Disease > > Selecting 1 or -1 according with the contrast or 0 if it was the other > thirth group. Also 0 in the EV's covariates (i.e. EV 4, 5, 6, 7, 8 and 9): > > EV1 Control EV2 Disease EV3Premuted > 1.000000e+00 0.000000e+00 -1.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > -1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > 1.000000e+00 -1.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > -1.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 -1.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 1.000000e+00 -1.000000e+00 0.000000e+00 0.000000e+00 > 0.000000e+00 0.000000e+00 0.000000e+00 0.000000e+00 > > However after all that, an error message apears when i saved: > > Problem with processing the model: Warning - design matrix uses different > groups (for different variances) but these do not contain "separable" EVs > for the different groups (it is necessary that, for each EV, only one of the > groups has non-zero values). > > I don't understand why the error, could you please help me with this? > > Thank you very much, > > Patricia. >