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Postdoctoral
Research Fellow
Structural
Biology of DNA Repair Complexes - Ref: 120
CR-UK DNA Repair Enzymes Group
Genome Damage and Stability Centre
School of Life Sciences
UNIVERSITY OF SUSSEX
A
Cancer Research UK-funded Postdoctoral position is available immediately in the
laboratory of Professor Laurence Pearl FRS to study the structural basis for
assembly and specificity of multi-protein complexes involved in the recognition
and repair of DNA breaks. The internationally renowned Genome Damage and
Stability Centre and the School of Life Sciences is very well equipped for all
aspects of modern structural biology, with state-of-the-art laboratories for
molecular biology, recombinant expression in bacterial and eukaryotic systems,
biochemistry, biophysics and X-ray crystallography. Excellent synchrotron
access (~ 2 days/month) is available through rolling beam-allocation programmes
at Diamond and ESRF.
Applicants
must have a PhD, and experience in recombinant expression and protein purification.
Experience of crystallization and X-ray crystallography would be an advantage.
Information on our previous work in this field can be found by searching PubMed
(pearl lh [au]).
The postholder will be responsible for expression, purification,
crystallization and structure determination of protein-protein and protein-DNA
complexes, and downstream biochemical characterisation.
Fixed term to end Sept 2012 in the first instance - Full Time
Salary: £29,853 - £35,646 per annum
Informal enquiries can be made to Professor Pearl [log in to unmask].
Closing date: 7 January 2011
For full details and how to apply see www.sussex.ac.uk/jobs
The University of Sussex is committed to equality of opportunity