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Dear colleagues,
Further to Richard Mainwaring-Burton‘s question I would be happy to get your feedback on Beckman Coulter’s statement with regard to the total bilirubin assay stating that haemolytic samples should be avoided. Is there any cut-off to be used in daily practice ? Rejecting samples with any degree of haemolysis would be a true disaster.
Thank you for your input.
Best regards,
Mike
Priv.-Doz. Dr. med. Michael Steiner
Medizinisches Labor Rostock
Suedring 81
D-18059 Rostock
Von: Clinical biochemistry discussion list [mailto:[log in to unmask]] Im Auftrag von Mainwaring-Burton Richard (South London Healthcare NHS Trust)
Gesendet: Donnerstag, 9. Dezember 2010 12:45
An: [log in to unmask]
Betreff: Roche Cobas direct bilirubin
Festive greetings
The kit insert for the current Cobas direct bilirubin admits to what I regard as serious interference from haemolysis :
Hemolysis: No significant interference up to an H index of 25 (approximate hemoglobin concentration: 15.6 ìmol/L (25 mg/dL)).
This represents a quite small degree of haemolysis.
Can I ask Roche-using members whether they are taking cognisance of the problem, and how they are managing the issues ?
with best wishes
Richard
Richard Mainwaring-Burton
Consultant Biochemist
South London Healthcare Trust
Queen Mary's Hospital
Sidcup, Kent, DA14 6LT
020-8308-3084
mob: 07831-739876
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