Hi All,<br><br>I have also noticed that the DCM10 model estimation process is taking _significantly_ longer to complete as compared to that run in the earlier SPM version.  This is the case even with a relatively simple model (with only 2 VOIs).  Has anyone else noticed this issue?  Can anything be done to improve the processing speed?<br>
<br>Thanks,<br>Emily Parks<br>
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    <p style="margin: 0px;">Dear DCMers,</p>

    <p style="margin: 0px;"> </p>

    <p style="margin: 0px;">I played a little bit around with DCM10, and
 found considerable difference compared to earlier versions of DCM when 
estimating an identical 6 regions motor network model. For example, 
connections which were strongly negative in the &quot;old DCM&quot; version 
(DCM.Ep) were strongly positive in DCM10 (1-state, bilinear, no 
stochastic). If I run more complex models in DCM10, it takes 6 (!) times
 longer than in earlier SPM8 versions...Coupling estimates in DCM10 are 
sometimes unusually big (close to 1.0). Is there any way to compare &quot;old
 DCMs&quot; with &quot;new DCMs&quot; to get a feeling of what has changed (and more 
importantly: what is correct)?</p>

    <p style="margin: 0px;"> </p>

    <p style="margin: 0px;">Best regards,</p>

    <p style="font-family: monospace; white-space: nowrap; margin: 5px 0px;">Christian<br>
    --------------------------------------------------<br>
    Dr. med. Christian Grefkes<br><br>
    Zentrum für Neurologie und Psychiatrie<br>
    Universität zu Köln<br>
    Kerpener Straße 62, 50924 Köln<br>
    phone: +49-221-4726-310<br>
    fax: +49-221-478-7005<br>
    <a href="http://neurologie-psychiatrie.uk-koeln.de/" target="_blank">http://neurologie-psychiatrie.uk-koeln.de/</a><br><br><br>
    Max Planck Institute for Neurological Research<br>
    Research Group Leader<br>
    Neuromodulation &amp; Neurorehabilitation<br>
    Gleueler Str. 50, 50931 Köln<br>
    phone: +49-221-4726-310<br>
    fax: +49-221-4726-298<br>
    <a href="http://www.nf.mpg.de/index.php?id=255" target="_blank">http://www.nf.mpg.de/index.php?id=255</a></p>
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