Is there any difference between the following methods of coregistration?

(1) realigning all functional images--coregister: using realigned T1 image (rs) as "reference image", mean functional image (means) as "source image", all the other functional images (rs) for "other images"-- normalize: "rmeans" functional image and all other functional images (rrs) selected and normalized onto EPI.nii template 

(2) realign all functional--coregister: choose mean functional as ref.image and structural as source-- normalize: select coregistered structural and normalize onto EPI.nii template.

Will the results obtained be the same in both cases??

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Sarika Cherodath
Graduate Student
National Brain Research Centre
Manesar, Gurgaon -122050
India