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Dear Kambiz, Yes, you can use SPM functions to analyse 2D time-frequency images. See http://www.ncbi.nlm.nih.gov/pubmed/15663957 In practice you can either convert your TF matrices to images using your own code or convert your TF data to Fieldtrip freq structure and then use spm_eeg_ft2spm to convert this struct to SPM dataset and subsequently convert it to images using the SPM function in 'Other'. Best, Vladimir Sent from my iPad On 8 Nov 2010, at 22:00, Kambiz Tavabi <[log in to unmask]> wrote: > I am trying to analyse 2D MEG data, within what I think fits the SPM frame work. I have time-frequency data computed using a Wavelet approach in each subject for a 3 x 2 design. I would like to carry out voxel-wise, fixed effects analysis of the time-frequency data. My goal is to identify time-windows showing effects of fixed factors on narrow band power. Is it possible to call specific SPM functions to carry out this type of analysis? Thanks in advance. > Kambiz