Hi



On 6 Oct 2010, at 15:38, Rodrigo Perea wrote:

Hello,
I am new in this field and I am very skeptical with the different matrix designs I've tried when I wanted to analyze a linear relationship case. I want to check the correlation between FA and age  in one time point in individuals of the same group with sex as a covariate.  

For example, lets suppose we have 10 individuals, my guesses were:


1. I demeaned the age and set up two contrasts.

Design.mat: In the first column it shows that all belong to Group1

Not quite - in the actual design matrix the first EV as shown below is modelling the overall group mean.

, 2nd colum is the demeaned age and the 3rd column my covaraite sex.

You would normally demean the 3rd EV as well - but in this case it won't matter.


/NumWaves 3
/NumPoints 47
/PPheights  1.000000e+00 2.558000e+01 1.000000e+00

/Matrix
1  -2.4  1
1  -2.8  1
1  5.7   0
1  -4.8  1
1  3.4   0

Desing.con: Since the 2nd EV is the one I want either a positive or negative relation, I ended doing this...

/Matrix
0 1 0
0 -1 0

Correct




Or my second guess
2.  I didnt set up the group values since all will be assigned to the same group. Thus, 1st column is the demeaned age and 2nd the covariate sex.

No - the first example is correct - note that the part of the Glm GUI where you enter group membership may be used in the modelling, but is NOT part of the design matrix.

Cheers.



Design.mat:
/Matrix
-2.4  1
-2.8  1
5.7   0
-4.8  1
3.4   0

Design.con

/Matrix
1 0
-1 0

Thanks in advance!



Rodrigo Dennis Perea
Neuro-Imaging Research Assistant
[log in to unmask]
Alzheimer's & Aging Program
The University of Kansas - School of Medicine



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