Dear SPMers, I am a new SPM8 user, I have a few questions related to FMRI_T0: 1. From the definition microtime onset is the first time bins at which the regressors are resampled to coincide with data aquisition. Can anyone help me, explain this in details. I still confusing what is microtime onset is. 2. From this SPM list I found 2 equation that can be use to calculate the microtime onset. fMRI_T0 = fMRI_T (TA/TR) (1/2) fMRI_T0 = (fMRI_T /TR)(TR - TA/2) I am not sure which equation is suitable with my data. My TR = 16s and TA = 2s. Stimulus will be given at-10s (As per attachment). I have tried to calculate my data using both equation but the results were not consistent. I would really appreciate some help with this matter. Thanks in advance [?][?] -- "the secret to real peace and happiness is to live in the present - to focus on the "NOW"."