Hi Stephen,

After consulting a bit on the issue, we are wondering if the issue with the lack of red lines (outlined in the previous message) could be due to a smoothing issue-- specifically having the kernel width set too high?  Would this have anything to do with your suggestions regarding the datatype or the data becoming demeaned?

I should add we did not mask in the original analysis.  Thank you again.

--Joe

On Thu, Aug 19, 2010 at 1:45 AM, Stephen Smith <[log in to unmask]> wrote:
Strange - possible either that the range of the denoised data has become tiny (in which case make sure the output from the denoising is in float datatype, and then multiply by (e.g.) 10000 in fslmaths) or that it's become demeaned (in which case add a mean value of (e.g.) 10000 back on (and remask)?

Cheers.


On 19 Aug 2010, at 07:07, Joseph P. Lowinske wrote:

Hi,

I am currently running two different analyses of our data:

1) unfiltered data

2) ICA-- denoised data (using MELODIC and visual inspection of individual components).

I am having some odd things come up in the registration of the denoised data only-- specifically in the registration of example_func to highres.


An example of the registration oddity can be found here:

http://www.flickr.com/photos/53161960@N04/4906281881/

versus the proper registration:

http://www.flickr.com/photos/53161960@N04/4906870188/


I have already looked over the filtered_func_data_denoised.nii.gz in fslview and I did not see any apparent problems.  This problem seems only to occur in roughly 25% of the subjects in our analysis.  Are there any ideas what might be happening here?  Thank you in advance!

--Joe



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Stephen M. Smith, Professor of Biomedical Engineering
Associate Director,  Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
+44 (0) 1865 222726  (fax 222717)
[log in to unmask]    http://www.fmrib.ox.ac.uk/~steve
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--
Joseph (Joe) Lowinske
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