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Hello Steve, I am sorry, perhaps I was not sufficiently clear, I know how to overlay the images (using fslview),but I want to know how to upsample back my stat image to standard image, I know that I have to use AppyXFM but I don’t know how. Since I use melodic I do not have for my group of subject a previous matrix to use with ApplyXFM. I have been trying the following command: a) flirt -in xxxx_tfce_tstat -ref MNI152_T1_2mm_brain -omat xxxx_tfce_tstat2 MNI.mat ( I tried also adding the options: cost corratio, search , dof and interp trilinear) b) flirt -in xxxx_tfce_tstat -ref MNI152_T1_2mm_brain -applyxfm -init xxxx_tfce_tstat2 MNI.mat -out xxxx_tfce_tstat2MNIspace The resulting image (xxxx_tfce_tstat2MNIspace) was considerably displaced. Also I tried fnirt after the first flirt fnirt --in=xxx_tfce_corrp_tstat --aff=xxxx_tfce_tstat2 MNI.mat --iout=xxxx_tfce_tstat2MNIspace --config=T1_2_MNI152_2mm --ref=MNI152_T1_2mm_brain The image was also displaced. 1) Could you please help me with this? 3) Regarding to my third question: If I create a mask from my stats image, Using fslview when I overlay the mask on another image (for instance my bg_image), the mask only displays one color, because the mask only has one value, (1s inside and zeros outside), I cannot keep within this mask the values that the original stats image has. For presentation purpose, my questions was: Is it possible to display that rendered map showing the ROI (mask) changing in a scale from red to yellow, according to the original values of that region that was masked (p-values in my case)? If so, How? Thanks a lot in advance. Lorena Jimenez.