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Hi - the output can be 0 if the data doesn't appear to have FDR-corrected significance…..
Cheers.


On 20 Sep 2010, at 09:56, Woodman, Sandra wrote:

> Hello,
> 
> Does anyone know if it looks like we are using FDR correctly.  For a mask, we
> used a non inverted image to make sure that we are using the same voxels as in
> our inverted image.  
> 
> 
> [purkinje:Left-Pallidum] (nmr-std-env) fdr -i
> FDRtest_contrast_CTRLaPATa_vox_vox_p_tstat2.nii.gz -m
> contrast_CTRLaPATa_vox_vox_p_tstat2.nii.gz -q 0.05 -v
> p-value image:: Size = (182,218,182,1)
> p-value image:: ROI Size = (182,218,182,1)
> p-value image:: Dims = (1,1,1,1)
> p-value image:: Minimum and maximum intensities are: 0.000199974 and 1
> Calculating FDR values
> Probability Threshold is: 
> 0
> 
> It looked like we had some good uncorrected p-values, but it doesn't make sense
> that we would get a probability threshold of 0.  Does anyone have any advice to
> check to see if we're doing anything wrong? Or if there is something else we
> could be doing/ using (flags etc.)?
> 
> Thank you!
> 
> Sandra
> 
> 
> 
> -----Original Message-----
> From: FSL - FMRIB's Software Library on behalf of Eugene Duff
> Sent: Thu 9/16/2010 5:06 AM
> To: [log in to unmask]
> Subject: Re: [FSL] Making a mask
> 
> Hi Sandra,
> 
> You're right, your mask is empty.  But following the instructions
> exactly, I could create a mask on your image, save it, and view it
> again in a new instance of fslview.  I guess you're not quite doing
> something right in creating the mask. Do you see the mask when you are
> drawing it?
> 
> Eugene
> 
> --
> 
> Centre for Functional MRI of the Brain (FMRIB) | University of Oxford
> John Radcliffe Hospital | Headington
> OX3 9DU | Oxford | UK
> 
> Ph: +44 (0) 1865 222 523 | Mob: +44 (0) 7946 362 059 | Fax: +44 (0) 1865 222 717
> 
> --
> 
> 
> 
> On 15 September 2010 22:27, Woodman, Sandra <[log in to unmask]> wrote:
>> Hello,
>> 
>> I have uploaded the image I wish to base the mask on:
>> FDRtest_contrast_CTRLaPATa_vox_vox_p_tstat2.nii.gz
>> 
>> And the image of the mask that I created:
>> FDRtest_contrast_CTRLaPATa_vox_vox_p_tstat2-mask.nii.gz
>> 
>> Refernce #: 987079
>> 
>> I know this mask was not created properly because when I used the paint bucket
>> tool to fill the mask with color to check that the mask was created...It
> filled
>> in the entire square.  What I'm thinking is that FSL is creating a mask that
>> includes the white space that surrounds the ROI in
>> FDRtest_contrast_CTRLaPATa_vox_vox_p_tstat2.nii.gz.  I also assume the mask
>> isn't working because when I feed it into fdr command I get a threshold= 0.
>> 
>>      [purkinje:Left-Pallidum] (nmr-std-env) fdr -i
>> FDRtest_contrast_CTRLaPATa_vox_vox_p_tstat2.nii.gz -m
>> FDRtest_contrast_CTRLaPATa_vox_vox_p_tstat2-mask.nii.gz -q 0.05
>>                        Probability Threshold is:
>>                        0
>> 
>> 
>> How do I specify in fslview to make a mask of just the ROI?  Do I need to cut
>> away the white space using another program?
>> 
>> This is what I have been using as directions for creating a mask:
>> http://fsl.fmrib.ox.ac.uk/fsl/fslview/masking.html
>> 
>> I appreciate you help!
>> 
>> Thank you,
>> 
>> -Sandra
>> 
>> Sandra Woodman
>> Mood and Motor Control Laboratory
>> Athinoula Martinos Center for Biomedical Imaging
>> Massachusetts General Hospital
>> 120 6th St.
>> Charlestown, MA 02129
>> Tel: 617-643-6245
>> Fax: 617-726-1351
>> Email: [log in to unmask]
>> 
>> 
>> 
>> -----Original Message-----
>> From: FSL - FMRIB's Software Library on behalf of Eugene Duff
>> Sent: Tue 9/14/2010 4:30 AM
>> To: [log in to unmask]
>> Subject: Re: [FSL] Making a mask
>> 
>> It's still a bit hard to tell.   Could you give more details, and/or
>> upload the mask and background image to
>> http://www.fmrib.ox.ac.uk/cgi-bin/upload.cgi
>> and send me the id..
>> 
>> Eugene
>> 
>> On 13 September 2010 21:09, Woodman, Sandra <[log in to unmask]> wrote:
>>> Hi Eugene,
>>> 
>>> When I load both the mask and the image, the mask is transparent even when we
>>> change the colors.  Why can't we see the mask?
>>> 
>>> Thank you!
>>> 
>>> -Sandra
>>> 
>>> Sandra Woodman
>>> Mood and Motor Control Laboratory
>>> Athinoula Martinos Center for Biomedical Imaging
>>> Massachusetts General Hospital
>>> 120 6th St.
>>> Charlestown, MA 02129
>>> Tel: 617-643-6245
>>> Fax: 617-726-1351
>>> Email: [log in to unmask]
>>> 
>>> 
>>> 
>>> -----Original Message-----
>>> From: FSL - FMRIB's Software Library on behalf of Eugene Duff
>>> Sent: Mon 9/13/2010 3:58 PM
>>> To: [log in to unmask]
>>> Subject: Re: [FSL] Making a mask
>>> 
>>> Hi Sandra -
>>> 
>>> I'm not exactly sure where the difficulty is, but once you've saved
>>> the mask as an image file, you can then load it as an overlay to any
>>> like-sized image.
>>> 
>>> Does that help?
>>> 
>>> Eugene
>>> 
>>> --
>>> 
>>> 
>>> On 13 September 2010 20:35, Woodman, Sandra <[log in to unmask]> wrote:
>>>> Hello!
>>>> 
>>>> I'm working on creating a mask and was wondering if anyone knew how to view
>>> the
>>>> mask once it had been created?
>>>> 
>>>> I used the steps in the following web page to create the mask:
>>>> 
>>>> http://fsl.fmrib.ox.ac.uk/fsl/fslview/masking.html
>>>> 
>>>> Now I want to make sure it is actually masking the correct area.
>>>> 
>>>> Thanks for you help!
>>>> 
>>>> -Sandra
>>>> 
>>>> Sandra Woodman
>>>> Mood and Motor Control Laboratory
>>>> Athinoula Martinos Center for Biomedical Imaging
>>>> Massachusetts General Hospital
>>>> 120 6th St.
>>>> Charlestown, MA 02129
>>>> Tel: 617-643-6245
>>>> Fax: 617-726-1351
>>>> Email: [log in to unmask]
>>>> 
>>>> 
>>>> 
>>>> -----Original Message-----
>>>> From: FSL - FMRIB's Software Library on behalf of Aditya Kumar Kasinadhuni
>>>> Sent: Mon 9/13/2010 2:34 PM
>>>> To: [log in to unmask]
>>>> Subject: [FSL] Thresholding in Post-stats of FEAT
>>>> 
>>>> Hi all,
>>>> 
>>>> I was wondering if there was some documentation that I can go through
>>> regarding
>>>> the various thresholding options enlisted in the post-stats section. In
>>>> particular I would like to know the difference between voxel and cluster
>>>> thresholding, and also I understand it makes cluster indices based on the
>>>> z-statistic threshold but how does FSL calculate this?
>>>> 
>>>> Thank you.
>>>> 
>>>> 
>>>> 
>>>> The information in this e-mail is intended only for the person to whom it is
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>>>> 
>>>> 
>>> 
>>> 
>> 
>> 
> 


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Stephen M. Smith, Professor of Biomedical Engineering
Associate Director,  Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
+44 (0) 1865 222726  (fax 222717)
[log in to unmask]    http://www.fmrib.ox.ac.uk/~steve
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