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Dear FSL experts: I am new user in FSL and I have tried TFCE and have several questions. 1: tbss_4_prestats threshold. bigger threshold generates less fibre branches in the mean FA skeleton image. what is appropriate (default 0.2). When I use 0.2 In my data, it seems to generate more fibre branches than displayed in the website. does the different threshold affact the statistical result? 2: Uncorrected P and PWE-Corrected results In uncorrected P result tbss_tfce_P_tstat, I found many significant regions (p < 0.05), but in PWE-corrected result tbss_tfce_corrp_tstat, I didn't founf any significant region (p < 0.05), is it possible? Here I used randomise -i all_FA_skeletonised -o tbss -m mean_FA_skeleton_mask -d design.mat -t design.con -n 5000 --T2 --V Thank you very much Best Shugao