Message

But Trans Bili should only be used when babies are 35 weeks or more and are therefore unlikely to weigh 1000g. Moreover, when was the last time we needed to get 8ml of blood to check a bili?

 

 

 

 


From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Reynolds Tim
Sent: 06 September 2010 17:12
To: [log in to unmask]
Subject: Re: Neonatal Jaundice

 

Because taking blood samples from neonates causes significant pain and iatrogenic blood loss. If these can be avoided to a large extent this is of benefit to the infant.

 

For a 1000g fetus, 8mL of blood is the equivalent of 1 pint blood loss from an adult.

 

60% of the most painful procedures applied to neonates are related to collecting samples. Neurobehavioral studoes show that these stimuli have a long-lasting effect on the responses to stimuli of oinfamts that have been on a NNU.

 

 

 

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-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Ian Barlow
Sent: 06 September 2010 17:03
To: [log in to unmask]
Subject: Re: Neonatal Jaundice

Why do we waste precious NHS resources on equipment that provides an inferior test result, (is recommended to be checked by the lab), and does not need to be done with critical urgency?

 

Ian

 


From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Jonathan Kay
Sent: 06 September 2010 16:09
To: [log in to unmask]
Subject: Re: Neonatal Jaundice

 

Yes, we're buying lots of transcutaneous bilirubinometers. Unfortunately it looks as if the first tranche won't have computerised communications available.

 

Does any one have a project or system that does?

 

(Our guess is that the CLT workload will initially go up, then go down... )

 

Jonathan

 

 

On 6 Sep 2010, at 15:55, O'Connor John (Royal Devon and Exeter Foundation Trust) wrote:

 

Dear Collective

 

Are labs following the recently published guideline on neonatal jaundice published in May this year?

 

Quite interesting that TC Bilirubin seems to be first line choice of measurement

 

BW John

 

 use a transcutaneous bilirubinometer in babies with a gestational age of

35 weeks or more and postnatal age of more than 24 hours

 if a transcutaneous bilirubinometer is not available, measure the serum

bilirubin

 if a transcutaneous bilirubinometer measurement indicates a bilirubin

level greater than 250 micromol/litre check the result by measuring the

serum bilirubin

 always use serum bilirubin measurement to determine the bilirubin

level in babies with jaundice in the first 24 hours of life

 always use serum bilirubin measurement to determine the bilirubin

level in babies less than 35 weeks gestational age

 always use serum bilirubin measurement for babies at or above the

relevant treatment threshold for their postnatal age, and for all

subsequent measurements

 do not use an icterometer.

 

The important bit is at the end

Research recommendation

What is the comparative accuracy of the Minolta JM-103 and the BiliChek when compared

to serum bilirubin levels in all babies?

Why this is important

Evidence: The accuracy of transcutaneous bilirubinometers (Minolta JM-103 and BiliChek)

has been adequately demonstrated in term babies below treatment levels (bilirubin

< 250 micromol/litre). New research is needed to evaluate the accuracy of different

transcutaneous bilirubinometers in comparison to serum bilirubin levels in all babies.

Population: Babies in the first 28 days of life. Subgroups to include preterm babies, babies

with dark skin tones, babies with high levels of bilirubin and babies after phototherapy.

Exposure: Bilirubin levels taken from different transcutaneous bilirubinometers. Comparison:

Bilirubin levels assessed using serum (blood) tests. Outcome: Diagnostic accuracy (sensitivity,

specificity, positive predictive value, negative predictive value), parental anxiety, staff and

parental satisfaction with test and cost effectiveness. Time stamp: Sept 2009

 

 

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------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/

------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/