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Can you re-send the attachment as jpg, or png, or pdf? Anything but docx Gandolla Marta wrote: > Hi everyone, > > I'd need some help about realignment parameters effect that seems > to be huge in the acquisition I will now describe. > We have a 30 secs block design, starting from rest. The patient is > performing active ankle dorsiflexion during on blocks. > We did the following preprocessing steps: > - realignment > - coreg > - normalize > - smooth (6mm) > > then we implemented the GLM with a 8 columns design matrix > (1-condition with the 30 secs block design, 2-7- realign param, 8- > baseline) and we found zero activation (p<0.01 FWE corrected). > we then chacked with the 2 columns design matrix (1-condition with the > 30 secs block design, 2- baseline) and we found a quite important > activation (fig.1). should we trust this activation? the realignemnt > param plot along with the block design protocol is shown in fig.2. is > it possible that all this effect depends on the correlation between > the realignment parameters and the condition column in the design > matrix? should trust only the design with the realignement parameters > as covariats of no interest? we are thinking in this case why we don't > see any activation... do we miss something? > > thanks for your help > best regards > marta