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Dear All, I've been thinking about the issue of modulation (non-linear versus affine+nonlinear) and it makes sense to only use the non-linear component alone. However, in DARTEL, flow fields are used and you it seems that SPM only allows you to warp by the determinant of the total. Could one "remove" the affine modulation effects by using the affine component of the transform from the segmentation procedure (assuming the end result is in MNI space) that same way its removed in VBM toolbox OR does the "affine" portion change when DARTEL is used? If so, is there a way to extract it? Best Regards, Donald McLaren ================= D.G. McLaren University of Wisconsin - Madison Neuroscience Training Program Office: (608) 520-0586 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (608) 520-0586 or email.