Dear all,
I am wondering if there are publications, where it is shown
that a ligand/substrate was not able to bind in one crystal
form of a protein, but was found in another crystal form.
In other words:
is there a case where the crystal packing interactions are
proofed to be responsible for non-binding of a substrate?
Thanks for any hints,
Stefanie
Dr. Stefanie Freitag-Pohl
Durham University
Chemistry Dept
South Road
Durham. DH1 3LE
Tel: 0191 3342143
Email: [log in to unmask]