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Hi Thilo, Thank you for this mail because I met the same problem just now. But I feel confused. You said ' if you have an even number, the even slices are measured first and then the odd slices '. According to this, I think if the slice order specification from top to bottom and nslice = 28, the sequence should be [nslice:-2:2 nslice-1:-2:1]. Is it a small mistake? -----Original Message----- From: SPM (Statistical Parametric Mapping) [mailto:[log in to unmask]] On Behalf Of Thilo Kellermann Sent: 2010年5月19日 18:30 To: [log in to unmask] Subject: Re: [SPM] Slice Time Correction Hi Ed, to make things a little more complicated: Usually you are right, that odd slices are measured first followed by the even ones. On a Siemens Trio machine, however, this is not always true (unless you use a self-programmed sequence). On a Trio the order depends on the number of slices - if you have an even number, the even slices are measured first and then the odd slices. Only if you have an odd number of slices the "normal" sequence (odd first, then even) is used. In this case the slice order specification from top to bottom should be: nslices = 28; [nlsices-1:-2:1 nslices:-2:1] The slices are numbered from bottom to top and the sequence gives the acquisition order. So if you are measuring from top to bottom and your number of slices is 28 on a Siemens Trio, the first slice you measure is no. 27, according to this numbering. In this case slices 1 and 28 are measured in the middle within a TR and the choice of either one should be ok. If you are more interested in dorsal parts of the brain 28 might be more appropriate. Unfortunately when acquiring slices interleaved you never know, when the most interesting slice is being measured. If the region you are interested in is spreaded over more than one slice, this region will be measured at quite different times within a TR anyway (namely with a delay of about TR/2). Good luck, Thilo On Monday 17 May 2010 19:53, Modestino, Edward J *HS wrote: > Hello, > I am in the process of attempting slice timing correction after completing > realignment. I have two questions: (1) I noticed that in the SPM8 manual > there is mention that slice timing correction will be removed in the > future. Why? > > (2) My EPI data is collect on a Siemens 3T MAGNETOM Trio in an interleaved > (odd slices first: odd 1:27 followed by even 2:28) sequence staring from > the top to bottom with 28 slices and a TR of 2 seconds. Slice timing is > not working. So, here are my specs. Please let me know if I have > something wrong: > > number of slices: 28 > TR: 2 > TA: 2-2/28 > Slice Order: I am choosing the option for interleaved top->bottom, so I > follow the input examples given there: TOP TO BOTTOM accoring to John > Christopher > interleaved top->down [nslices:-2:1, nslices-1:-2:1] > 28:-2:1, 28-1:-2:1 > displays [28 26 24 22 20 18 16 14 12 10 8 6 4 2 27 25 23 21 19 17 15 13 11 > 9 7 5 3 1] > > Shouldn't this order be the following instead [1 3 5 7 9 11 13 15 17 19 21 > 23 25 27 2 4 6 8 10 12 14 16 18 20 22 24 26 28] > > What does it mean that bottom slice = 1, as we are going top to bottom and > the top slice is 1? How can the bottom slice be 1? > > Reference slice: 2 (or I could use slice 27) > > Thanks, > Ed Modestino > > Edward Justin Modestino, Ph.D. > Postdoctoral Research Associate > Ray Westphal Neuroimaging Laboratory > Division of Perceptual Studies > Department of Psychiatry and Neurobehavioral Sciences > University of Virginia -- Thilo Kellermann RWTH Aachen University Department of Psychiatry and Psychotherapy JARA Translational Brain Medicine Pauwelsstr. 30 52074 Aachen Germany Tel.: +49 (0)241 / 8089977 Fax.: +49 (0)241 / 8082401 E-Mail: [log in to unmask] __________ Information from ESET NOD32 Antivirus, version of virus signature database 5127 (20100519) __________ The message was checked by ESET NOD32 Antivirus. http://www.eset.com __________ Information from ESET NOD32 Antivirus, version of virus signature database 5133 (20100520) __________ The message was checked by ESET NOD32 Antivirus. http://www.eset.com