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Dear Bing, Cluster inference works best when you have a search volume that is large relative to the smoothness. For just a 10mm radius SVC region, I wouldn't expect cluster inferences to be of any use at all. For such small regions I would stick with peak/voxel inferences. -Tom On Thu, May 27, 2010 at 7:38 PM, Bing Ye <[log in to unmask]> wrote: > Dear SPMers: > > I want to use small volume correction (SVC) for the brain activation level. > I have encountered an issue, after using the SVC, the puncorrected value at > the cluter-level is higher than before (e.g. p=0.06 after using the SVC , > whereas before is 0.02. ) , but the p corrected-level is significant after > SVC at cluster-level. I do not know the reason, is it supposed to be like > that some times? > > What should I be looking at after SVC, cluster-level p uncorrected or p > corrected or voxel-level p fwe-corrected or p fdr-corrected, and at what p > level ( p = 0.05)? > > I entered 10 mm for the radius value > > Can anyone let me know? > > Thank you in advance. > > Bing > -- ____________________________________________ Thomas Nichols, PhD Principal Research Fellow, Head of Neuroimaging Statistics Department of Statistics & Warwick Manufacturing Group University of Warwick Coventry CV4 7AL United Kingdom Email: [log in to unmask] Phone, Stats: +44 24761 51086, WMG: +44 24761 50752 Fax: +44 24 7652 4532