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Hello FSL experts: After all I was able to run the dual_regression script and I got the following outputs: dr_stage_1, dr_satage_2 at this time I was able to got the output "dr_satate_3" for my 4 contrasts. it looks like this: dr_stage3_ic0000_tfce_corrp_tstat1.nii.gz dr_stage3_ic0000_tfce_corrp_tstat2.nii.gz dr_stage3_ic0000_tfce_corrp_tstat3.nii.gz dr_stage3_ic0000_tfce_corrp_tstat4.nii.gz and so on..... for each components The situation now is that when I see the folder "script+logs" I still have problem because it still produces empty drA.*** files, drB*** files, the drC.***. and drD.e.*** files. Only the drDo files have the following information: randomise options: -i grot/dr_stage2_ic0000 -o grot/dr_stage3_ic0000 -m grot/mask -d design.mat -t design.con -n 500 -T -V Loading Data: ************************************ Data loaded 9.07514e+09 permutations required for exhaustive test of t-test 1 Doing 500 random permutations Starting permutation 1 (Unpermuted data) Starting permutation 2 Starting permutation 3 and so on...... Repeating that four time (I used four contrast) My questions are: 1) Why those files are empty (drA, drB. drC and drD.e) ? :-( Are not those files necessary to do the permutation tests? 2)I have been researching the archives but I still have this question: What is better that you choose the number the components or to allow FSL to choose the numbers of them? if the former is better How do you choose a good number? I greatly appreciate any hint Thank you very much in advance for all of your help BTW: I know what means "tfce" but What does means "corrp" Lorena Jimenez Castro, MD Postdoc Fellow