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Maybe your mask is not a binary mask. On 4/21/2010 2:10 PM, Fred Sanders wrote: > Dear SPM experts, > > When using an explicit mask with a 2nd level analysis, I get an error > during the model estimation step - the error states "No significant > voxels." I only get this error when I use an explicit mask. Without > the mask, the model estimation works fine. Looking thru other posts, > it looks like other users have had a similar problem, but I could not > find any solutions (outside of making sure my SPM8 has the most recent > updates, which it does.) Any suggestions? > > Thanks!! > > Fred