Dear Friends of SPM, I was doing a simple 2nd level analysis, paired T test to be specific. The design matrix looks fine before I ran the spm5 estimation, please see the attached beforeestimate.jpg. However, after the estimation the design matrix changed somehow, please see the afterestimate.jpg, it turned a little bit gray but not clear cut black/white. I am wondering is it just a graphic artifact of spm5, or I did something wrong? Or spm5 adjusted my original design matrix because of some weakness of my data? Thanks in advance. Xin Xin Chen Ph.D. Brain and Behavior Discovery Institute Medical College of Georgia