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Hi,
     There shouldn't be a problem using your ROI as a mask, as long as the ROI is derived from some prior belief about areas of interest ( e.g. I'm only interested in results for white-matter voxels ).

Many Regards

Matthew


> Hi FSL experts,
> 
> I'm looking to perform a 1 sample t-test using binary mask output from another analysis (classification masks). Is this valid with randomise, the results look reasonable but I have a sneaking suspicion I'm breaking the rules a bit? 
> 
> All the best
> Jonathan
>