I don't see why not. You should check the before and after output of eddy_correct to make sure it is improving things (view the timeseries as a movie in FSLView). Peace, Matt. _____ From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf Of Moran Artzi Sent: Monday, April 12, 2010 11:22 AM To: [log in to unmask] Subject: Re: [FSL] High b value diffusion data Hi, Thanks for your replay We have data (10-11 slices) acquired on the coronal orientation, using b value of 12000 mm/sec2 and 45 gradient directions. We would like to have FA, MD and Eigen's (1-3) maps additional to probabilistic and displacement maps Can it be done? Moran On Mon, Apr 12, 2010 at 6:57 PM, Matt Glasser <[log in to unmask]> wrote: Yes it is possible. What kind of data do you have? The biggest issue I have encountered is lower SNR/more difference in contrast between DWIs and b0s, which can lead to a poorer eddy_current and subject motion correction. Peace, Matt. -----Original Message----- From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf Of Moran Artzi Sent: Monday, April 12, 2010 10:20 AM To: [log in to unmask] Subject: [FSL] High b value diffusion data Hi, Is it possible to analyzed High b value diffusion data using FSL? Otherwise dose any one familiar with any (free) tool, source code to preformed q-Space analysis? Many thanks Moran