Why do we try and report "Estimate of what the total calcium would be if the albumin were something else" rather than "Estimate of ionised calcium". Is it only for historical reasons?
"Estimate of ionised calcium" woud be more consistent with pathophysiological understanding and with results from blood gas analysers.
Jonathan
On 16 Apr 2010, at 12:28, Maguire, Gerald wrote:
> If you’ve got your formula correct (and many people won’t), you can certainly use it at an albumin of 9 g/l.
>
> See some old (unpublished) data below
>
> Gerald
>
> <image001.gif>
>
> -----Original Message-----
> From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Lee, Lynn
> Sent: 16 April 2010 10:49
> To: [log in to unmask]
> Subject: Albumin Adjusted Calcium.
>
> Hello,
>
> Could any of the list members tell me if they have an Albumin lower limit restriction when calculating Corrected Calcium, using the formula:
>
> Ca(corrected, mmol/L) = Ca( measured, mmol/L) + {(40 – (Albumin) x 0.02}
>
> We use the BCP method for measuring albumin and an Arsenazo-III dye for Calcium.
>
> I would be interested in your comments as to how accurate you consider this formula to be at Albumin levels less than 25g/L and at what level an ionized Calcium would be more appropriate.
>
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