Thank you for the quick reply Mathew. Thanks also for pointing out the MarsBaR e-mail list.<br><br>Regards<br>Harsha<br><br><div class="gmail_quote">On Fri, Mar 26, 2010 at 3:40 AM, Matthew Brett <span dir="ltr">&lt;<a href="mailto:[log in to unmask]"><a href="/cgi-bin/wa-jisc.exe?LOGON=A3%3Dind1003%26L%3DSPM%26E%3Dquoted-printable%26P%3D6195415%26B%3D--0016e6816cbc8d9ca90482ada2cf%26T%3Dtext%252Fhtml%3B%2520charset%3DISO-8859-1%26pending%3D" target="_parent" >[log in to unmask]</a></a>&gt;</span> wrote:<br>
<blockquote class="gmail_quote" style="margin: 0pt 0pt 0pt 0.8ex; border-left: 1px solid rgb(204, 204, 204); padding-left: 1ex;">Hi,<br>
<br>
I think you want the MarsBaR list for this one....<br>
<div class="im"><br>
&gt; 1. While using SPM5,for extracting a fMRI timecourse (eigenvariate) one has a option of adjusting the timecourse for a specified F-contrast. What excatly does this &quot;adjusting&quot; do? Specifically, does it include some form of mean centering and hemodynamic deconvolution? I have noticed that subjecting an adjusted timecourse to simple deconvolution in the PPI module of SPM5 does not further change it in anyway.<br>

<br>
</div>I believe that the adjustment regresses out the effects not contained<br>
in the F contrasts.   These effects will typically include, as you<br>
say, the mean, but not hemodynamic convolution.<br>
<div class="im"><br>
&gt; 2. Since I would like to extract the MEAN timecourse from a spherical VOI rather than the eigenvariate, I have tried using MarsBaR. Is it possible to adjust the extracted timecourse for an F-contrast in MarsBar? If so how?<br>

<br>
</div>You could use the spm_graph option in the results menu; that is<br>
essentially the same as the SPM algorithm...<br>
<br>
Best,<br>
<font color="#888888"><br>
Matthew<br>
</font></blockquote></div><br>