Hi Bentata, You may want to have a look at the following 2 papers. It may not be exactly what you want, but it will definitely introduce you to the approach utilizing prior information while dealing with PET data processing. Kristof Baete, Johan Nuyts<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/n/Nuyts:Johan.html>, Wim Van Paesschen<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/p/Paesschen:Wim_Van.html>, Paul Suetens<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/s/Suetens:Paul.html>, Patrick Dupont<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/d/Dupont:Patrick.html>: Anatomical-based FDG-PET reconstruction for the detection of hypo-metabolic regions in epilepsy. IEEE Trans. Med. Imaging 23<http://www.informatik.uni-trier.de/%7Eley/db/journals/tmi/tmi23.html#BaeteNPSD04>(4): 510-519 (2004) Johan Nuyts<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/n/Nuyts:Johan.html>, Kristof Baete, Dirk Beque<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/b/Beque:Dirk.html>, Patrick Dupont<http://www.informatik.uni-trier.de/%7Eley/db/indices/a-tree/d/Dupont:Patrick.html>: Comparison between MAP and postprocessed ML for image reconstruction in emission tomography when anatomical knowledge is available. IEEE Trans. Med. Imaging 24<http://www.informatik.uni-trier.de/%7Eley/db/journals/tmi/tmi24.html#NuytsBBD05>(5): 667-675 (2005) best regards, sid. On Tue, Mar 2, 2010 at 12:11 PM, Bentata Réda <[log in to unmask]> wrote: > Dear member,as part of my studies I have for project, the segmentation of > image TEP based on an anatomical atlas. > The final goal of the project is the realization of an application, > allowing the segmentation of a volume PET using an anatomical atlas. > I have not chosen the kind of image yet which I am going to work, but I > think of working on the brain images. > The first step of my project was the loading and the visualization of a > volume (IMG + HDR), Having for a long time study this format, I was able to > create a little software allowing to display the frames of a volume under > the differents views (sagittal, axial and coronnal). > Now, I have to study the process of segmentation, I would like to have your > opinions and suggestions on the various methods (algorithms) allowing to > realize the segmentation basing on an anatomical atlas. > > Thank you in advance for your answers! > Bentata Réda. > >