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Stephen J. Fromm wrote: > On Tue, 2 Mar 2010 19:21:22 -0600, Misha Koshelev <[log in to unmask]> > wrote: > > Why do you think regressors are always orthogonalized? > I have attached the file spm_get_ons.m for SPM2. On line 224-226 it reads: % orthogonalize inputs %--------------------------------------------------------------- u = spm_orth(u); Per my lab members advice, this is the line where orthogonalization of regressor is done. In fact, he toggles this line (or not) to determine whether or not his regressors are orthogonalized (if commented out - no orthogonalization). Is this not the case? Thank you Misha Koshelev -- Misha Koshelev MD/PhD Student Human Neuroimaging Laboratory One Baylor Plaza S104 Baylor College of Medicine Houston, TX 77030